How Much Does Ocrevus Cost?
Ocrevus’ out-of-pocket cost can vary based on insurance coverage, location, and site of care. However, research from AHIP indicates that outpatient infusion centers often provide a more affordable option, averaging $7,000 less than hospitals, where facility fees and higher service charges drive up costs.
Additionally, the Genentech Patient Foundation may offer assistance for patients who are uninsured or unable to afford their share of the cost.
How Is Ocrevus Administered?
Ocrevus is typically given as two initial 300 mg infusions two weeks apart, followed by a single 600 mg infusion every six months. Patients should plan for a total appointment time of about 5.5 hours for each infusion.
Pre-Infusion (30–60 Minutes)
Before starting Ocrevus, patients typically receive premedication (corticosteroid; antihistamine), which can be given by mouth or through an IV. This step helps reduce the chance of experiencing infusion-related reactions.
Infusion (2.5 hours for initial infusions; 3.5 hours for maintenance doses)
During the infusion, patients are seated in a comfortable chair while a thin needle is placed in the arm to deliver Ocrevus through an IV drip. An automatic pump carefully regulates the rate of administration. If any infusion reactions occur, the healthcare team may pause or slow the infusion to manage symptoms.
Post-Infusion (At Least 1 Hour)
Once the Ocrevus infusion is complete, patients remain under observation for at least one hour. This allows the healthcare team to watch for any side effects or issues that may arise following treatment.
Future 2-Hour Infusions
After tolerating the initial and maintenance infusions without serious reactions, if approved by their referring provider, some patients may qualify for a shorter, 2-hour infusion for future treatments. The total dose of Ocrevus remains the same but is administered more quickly.
Who Makes Ocrevus?
Ocrevus is manufactured by Genentech, a member of the Roche Group.